Background: Desmoplastic fibroblastoma (collagenous fibroma) is a rare fibrotic tumor that presents as a firm, slowly growing, painless mass. In order to deepen the understanding of the diagnosis and differential diagnosis of desmoplastic fibroblastoma, we planned to analyze the clinical, radiological, and histopathological features and the outcome of desmoplastic fibroblastoma. Case Report: The authors report a case of a 48-year-old woman with a hard, slightly mobile nodule with imprecise limits in the right mandibular angle, with 9 month evolution. Ultrasound showed a hypoechoic, solid nodule in the superficial portion of the parotid gland. Full parotidectomy was performed by detection of a contiguous nodule at the deep plane, adhering to the buccal branch of the facial nerve. Histology revealed a collagen fibroma. Conclusion: Awareness of this rare lesion arising in atypical location such as the parotid is required, as diagnosis and management can be challenging.