Background: Varicella, or chickenpox, is a common viral infection caused by the varicella-zoster virus (VZV). While typically self-limiting, it can lead to severe complications, particularly in immunocompromised individuals. Haematological abnormalities, such as thrombocytopenia, are well-documented, but pancytopenia remains extremely rare, especially in immunocompetent children. Case Report: We present a case of an 11-year-old female with varicella complicated by pancytopenia. The patient developed high fever, vesicular rash, hepatosplenomegaly, and altered sensorium, requiring hospitalization. Laboratory investigations confirmed pancytopenia without atypical cells or hemolysis. The patient received intravenous acyclovir and ceftriaxone, leading to gradual recovery. Conclusion: Pancytopenia as a complication of varicella is rare and may be underreported. Early diagnosis and supportive management are crucial for favourable outcomes.