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Abstract
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Introduction: Ligneous conjunctivitis is rare form of conjunctivitis characterized by woody fibrinous membranes. Plasminogen deficiency has been introduced as the most common cause and formation of membrane is the result of impaired wound healing process. Case Report: We present a 4-month-old male infant with chronic membranous conjunctivitis. Multiple scrapping of membranes were performed with no improvement. Fibrinous membranes were also seen on nasal cavity and upper gingiva. After his blood revealed plasminogen blood levels of 11.9% (normal: 75-135%), diagnosis of ligneous conjunctivitis due to plasminogen deficiency was obtained. Treatment was then changed to topical fresh frozen plasma and heparin. Dramatic resolution of membranes was observed after 15 months therapy combined with membranes scraping. Conclusion: Ligneous conjunctivitis is rare manifestation of plasminogen deficiency that occurs sporadically where local infection and multiple surgeries might act as trigger to induce fibrinous membranes. Topical heparin and FFP could treat the disease successfully.
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Keywords :
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Conjunctivitis, Plasminogen, Heparin, Nasal Cavity, Gingiva, Infant, Humans.
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