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Journal of Case Reports
A Rare Case of Metastasis of Merkel Cell Carcinoma to the Jejunum

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Yuta Ogura1, Takeharu Enomoto1, Shinya Mikami1, Hiroyuki Hoshino1, Akiyoshi Noda1, Osamu Saji1, Tsunehisa Matsushita1, Shinya Ishigouoka2, Masaki Yamashita2, Saeko Naruki3, Takashi Fujino3, Tetsu Fukunaga1, Takehito Otsubo1
1Division of Gastroenterological and General Surgery, 2Division of Gastroenterological Internal Medicine, 3Department of Pathology; St. Marianna University School of Medicine, Kawasaki, Japan.
Corresponding Author:
Dr. Takeharu Enomoto
Email: takeharu@marianna-u.ac.jp
Received: 31-MAR-2016 Accepted: 08-JUN-2016 Published Online: 15-AUG-2016
DOI: http://dx.doi.org/10.17659/01.2016.0091
Abstract
We describe a rare case of metastasis of Merkel cell carcinoma (MCC) to the jejunum. The patient was a 79-year-old man with a chief complaint of dizziness and palpitation. He sought medical attention 3 days after the dizziness and palpitation had manifested and was admitted to our hospital. His medical history included MCC, prostate carcinoma, abdominal aortic aneurysm, and stroke. We performed an enteroscopic examination and found a neoplastic lesion in the upper jejunum. Evidence of bleeding led us to perform emergency laparoscopic surgery. Pathologic examination revealed small round cells forming a nodule, and immunostaining for epithelial marker CK20 and neuroendocrine marker synaptophysin were positive. The final diagnosis based on histopathologic examination of the resected jejunal tumor was metastatic MCC. Such metastasis is indeed rare, and we consider our patient’s tumor in light of the literature. 
Keywords : Dizziness, Jejunum, Laparoscopy, Merkel Cell Carcinoma, Skin Neoplasms, Stroke.
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