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Abstract
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The cases of esophageal cancer are rapidly increasing worldwide and the highest rates found in Southern and Eastern Africa and Eastern Asia. The treatment option for esophageal cancer is either surgical or non-surgical. We report a 70 year old obese female without any concomitant disease diagnosed with locally advanced esophageal carcinoma with metastasis (T4N1M0). Patient was treated with concurrent chemoradiation along with nimotuzumab 200 mg. The chemotherapy was with cisplatin in the dose of 35 mg/m2 weekly for a period of seven cycles and radiotherapy was with a total radiation dose of 59.5 Gy. The patient responded well to the combination therapy by showing a near absence of tumor lesion, which was evident on a repeat, post treatment whole body PET-CT Scan. Patient tolerated the therapy well without any significant adverse effects. Nimotuzumab was found effective with chemoradiotherapy in treatment of esophageal squamous cell carcinoma. |
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Keywords :
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Oesophageal Neoplasms, Squamous Cell Carcinoma, Nimotuzumab, Cisplatin, Chemoradiotherapy.
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